The WHO added the advisor because of other risk associated with taking the drug, not that those who aren't severely or critically shouldn't be taking it.
Although corticosteroids can benefit those with severe COVID-19, the Mayo Clinic warns of potential adverse effects associated with the drug, including elevated pressure in the eyes (glaucoma), fluid retention, high blood pressure and increased risk of other infections. As a result of these risks, WHO added to their guidance that they “suggest not to use corticosteroids in the treatment of patients with non-severe COVID-19.” Cutrell says that there’s a possibility that use of the drugs may cause a “flare up” of other infections, but that researchers will have to “watch and see” as more people are given the treatment.
Once a patient requires oxygen it is given to halt the chances of the cytokine storm. Once given oxygen it's evidence enough the virus may accelerate, taking the steroid halts that chance.
“The survival benefit is clear and large in those patients who are sick enough to require oxygen treatment, so dexamethasone should now become the standard of care in these patients.”
Corticosteroids, it seems, are capable of quieting down a reaction that can quickly turn deadly. “The cytokine storm is just kind of saying it's gotten out of control,” says Cutrell. “And so the steroids are kind of a blunt instrument, but it's a broad way of kind of damping down that inflammation.”
It was during the study they found it also reduced deaths for critically ill patients:
The RECOVERY study, which was initially criticized for being shared only via press release, also found a 30 percent reduction in the mortality rate of severely ill COVID-19 patients given dexamethasone. At the time, the authors hailed it as “groundbreaking.”
So people who are sick enough for oxygen but not at a critical or severe level of the illness are given the drug so that they don't reach severe or critical status.
The WHO added the advisor because of other risk associated with taking the drug, not that those who aren't severely or critically shouldn't be taking it.
Once a patient requires oxygen it is given to halt the chances of the cytokine storm. Once given oxygen it's evidence enough the virus may accelerate, taking the steroid halts that chance.
It was during the study they found it also reduced deaths for critically ill patients:
https://www.yahoo.com/lifestyle/corticosteroids-deemed-an-effective-inexpensive-and-safe-treatment-for-severe-covid-19-230437532.html
So people who are sick enough for oxygen but not at a critical or severe level of the illness are given the drug so that they don't reach severe or critical status.
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